Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate) 0.729 0.154
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846
SLC5A7 Q9GZV3 solute carrier family 5 member 7 Transporter 1.5E-02 0.597 0.654
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.539 0.808
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
S100A10 P60903 S100 calcium binding protein A10 Calcium-binding protein 0.17 0.528 0.769
RELN P78509 reelin 1.00 0.515 0.731
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PROK2 Q9HC23 prokineticin 2 Signaling 1.4E-02 0.555 0.769
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846